INGREDIENTS BACKED BY SCIENCE
INGREDIENTS BACKED BY SCIENCEOur proprietary blends feature scientifically backed active ingredients that have been proven to addressing all 12 key causes of biological ageing
Gold Standard Clinical Research
In the development of our proprietary products, we adopted the gold standard in clinical research when
evaluating the safety and effectiveness of treatments adhered to a set of three rigorous scientific criteria before any molecule was considered for our formula.
The seven powerful ingredients in DAILY
NMN
NMN, an abbreviation for nicotinamide mononucleotide, is a derivative of vitamin B3 & serves as a precursor to NAD+ (nicotinamide adenine dinucleotide), a crucial coenzyme found in every living cell. NAD+ plays a pivotal role in shielding our bodies from the impacts of ageing and diseases. As we grow older, our NAD+ levels drop. This is where NMN supplementation helps - by addressing the natural depletion of NAD+ in our systems, thereby restoring its levels and counteracting the multiple signs of cellular ageing.
Resveratrol
Resveratrol is a natural compound found in certain plants, especially in the skin of red grapes, red wine, peanuts, and some berries. It has garnered a lot of attention for its potential health benefits and it is believed to promote longevity and combat ageing by protecting cells from damage, improving cellular function, and reducing inflammation.
Quercetin
Quercetin is a plant flavonoid that's found in a variety of foods, including apples, onions, berries, and red wine. It supports the immune system and aids in the removal of zombie-like senescent cells.
Pterostilbene
Pterostilbene, a compound discovered in blueberries. It is a potent antioxidant and has anticancer properties. Pterostilbene acts at the cellular level to address inflammaging and aids in maintaining a stable epigenome and DNA.
Spermidine
Spermidine is a naturally occurring polyamine compound that is found in all living cells, including plants, animals, and microorganisms. Spermidine-rich foods include soybeans, wheat germ, and aged cheeses. Spermidine has been studied for its potential anti-ageing effects, and it appears to combat several hallmarks of ageing.
Alpha-ketoglutarate (AKG)
Alpha-ketoglutarate (AKG) extends lifespan and healthspan in different species. In humans, alpha-ketoglutarate has shown to protect cells against damage and stressors. Alpha-ketoglutarate supports a healthy metabolism and a healthy epigenome.
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Glycine
Glycine is a non-essential amino acid that plays various roles in the body and has been demonstrated to prolong life in various organisms. In humans, elevated glycine levels correlate with heart health, fighting cellular-level inflammaging , aiding
glucose metabolism and activating autophagy.
How do DAILY Ingredients Combat the Hallmarks of Ageing?
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Cellular Energy Production - NMN supplementation is thought to boost NAD+ levels, potentially improving cellular energy production.
DNA Repair: Increasing NAD+ levels through NMN may support better DNA repair processes and boost cellular function.
Sirtuin Activation: NMN is believed to activate a group of proteins called sirtuins, which may help slow down the ageing process and promote longevity.
Metabolic Health: NMN supplementation can improve metabolic functions, such as insulin sensitivity and fat metabolism.
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Genomic Instability: Quercetin has been shown to have DNA-protective properties, potentially helping to maintain the integrity of the genome.
Telomere Attrition: While the evidence is still emerging, some studies suggest quercetin might influence telomere length, thereby possibly influencing cellular ageing processes.
Mitochondrial Dysfunction: Quercetin has been found to support mitochondrial function, which tends to decrease with age.
Cellular Senescence: Quercetin, has been shown to help remove senescent cells, a process termed "senolytics". Eliminating senescent cells might improve tissue function and delay age-related diseases.
Chronic Inflammation: Quercetin has anti-inflammatory properties and can modulate inflammatory pathways, potentially reducing this age-related inflammation.
Oxidative Stress: Quercetin's antioxidant properties can help reduce oxidative stress and the associated damage.
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Oxidative Stress: Pterostilbene is an antioxidant, which means it can help combat oxidative stress. It helps neutralize free radicals, reducing
cellular damage and the ageing effects associated with oxidative stress.Inflammation: Pterostilbene has been studied for its anti-inflammatory properties, potentially reducing the inflammatory processes that contribute to ageing and age-related diseases.
DNA Damage: Pterostilbene's antioxidant properties may help protect DNA from damage caused by oxidative stress, reducing the rate of DNA-related ageing.
Cellular Senescence: Pterostilbene may have a role in promoting healthy cell function and possibly delaying cellular senescence.
Epigenetic Changes: Some research suggests that pterostilbene may influence epigenetic modifications, potentially impacting ageing-related gene expression patterns.
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Cellular Senescence: Spermidine has been shown to induce autophagy, a process that helps remove damaged cellular components, including senescent cells, which are associated with ageing and age-related diseases.
Oxidative Stress: Spermidine acts as an antioxidant, helping to reduce the harmful effects of oxidative stress by neutralizing free radicals and protecting cells from oxidative damage.
Inflammation: Spermidine has anti-inflammatory properties and may help reduce chronic inflammation, which is a common feature of ageing and age-related
diseases.DNA Damage: Spermidine can support DNA stability and repair mechanisms, potentially reducing the accumulation of DNA damage over time.
Mitochondrial Dysfunction: Spermidine may improve mitochondrial function, which
plays a crucial role in energy production and cellular health. Mitochondrial dysfunction is a hallmark of ageing.Epigenetic Changes: Some research suggests that spermidine may influence
epigenetic processes, helping to maintain proper gene expression patterns as we age. -
Mitochondrial Dysfunction: Glycine can be protective for the mitochondria.. Studies suggest that glycine supplementation might improve mitochondrial efficiency and reduce the production of reactive oxygen species (ROS), which are harmful molecules that can damage cellular structures.
Proteostasis: Glycine is crucial for the synthesis of glutathione, a major antioxidant in the body that protects cells from oxidative stress and can
influence proteostasis - the balance and regulation of proteins within cells.Nutrient Sensing: Glycine might have a role in pathways like the mTOR pathway, which is involved in sensing nutrient availability and regulating cell growth. Some studies, primarily in animals, suggest that glycine restriction can extend lifespan by modulating these pathways,
Chronic Inflammation: studies suggest that glycine has anti-inflammatory properties, potentially helping combat this hallmark.
Stem Cell Exhaustion: Glycine might support the health and function of stem cells, which are cells that can differentiate into various cell types and replenish tissues. Stem cell function often declines with age.
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Antioxidant Properties: it can help protect cells from damage caused by harmful molecules and may play a role in slowing the ageing process.
Heart Health: Resveratrol has been studied for its potential to improve cardiovascular health - lowering blood pressure, and improve the function of blood vessels.
Anti-Inflammatory: Resveratrol has anti-inflammatory properties that can help combat chronic inflammation, associated with various age-related diseases.
Cancer Prevention: Evidence suggests resveratrol may have anti-cancer properties by inhibiting the growth of cancer cells and reducing the spread of tumours.
Brain Health: Resveratrol has also been investigated for its potential to protect brain and may have a role in reducing the risk of neurodegenerative diseases like Alzheimer's and Parkinson's.
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Energy Production and Mitochondrial Health: AKG plays a crucial role in the Krebs cycle, helping to produce energy within cells. It supports mitochondrial health and function, which is vital since mitochondrial dysfunction is a hallmark of aging. By promoting efficient energy production, AKG helps maintain cellular vitality and can reduce the decline in mitochondrial function seen with aging.
Reducing Oxidative Stress:AKG can help decrease oxidative stress by participating in cellular processes that minimize the damage caused by reactive oxygen species (ROS). Lowering oxidative stress is important for protecting cells from damage that accumulates over time, contributing to aging and age-related diseases.
Stem Cell Support Evidence suggests that AKG may support stem cell health and functionality. Stem cells have the ability to turn into different types of cells and are essential for tissue regeneration and repair. Maintaining stem cell health with age can help promote tissue renewal and combat aging.
Inflammation Reduction: Chronic inflammation is another key hallmark of aging, and AKG has been shown to possess anti-inflammatory properties. By reducing inflammation, AKG can potentially decrease the risk of developing chronic age-related conditions.
Epigenetic and Hormonal Effects: AKG may influence epigenetic markers and hormonal pathways that are associated with aging. It can impact gene expression and has been linked to the extension of lifespan and healthspan in various organisms by modulating these pathways.
Promoting Protein and Amino Acid Metabolism: AKG is involved in the metabolism of amino acids, which are the building blocks of proteins. Proper protein and amino acid metabolism is crucial for the body's maintenance and repair mechanisms, and AKG's role in this process can help support overall health and longevity.
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